Biomarkers we prioritize on this medication
Baseline liver markers before and during use
View marker →Kidney function, reported concern at high doses
View marker →Thyroid dysfunction reported with high-dose injectable use
View marker →Direction is how the marker usually moves on this class of medication, not a target set for you. Once you are prescribed, your own values, ranges and trend appear in the app.
Medicine information
Glutathione Injections deliver the body's master antioxidant directly into the bloodstream to support detoxification, immune health and protection against oxidative stress.
Commonly prescribed for
Active ingredients
Glutathione (Reduced L-Glutathione)
A subcutaneous injection. Refrigerate, protect from light, and follow the pharmacy label. Dispose of needles in a sharps container.
There is no FDA-approved injectable glutathione product and no approved label to cite, so what follows comes from published studies and from regulatory advisories about compounded and unregulated use. Injection site pain, redness and swelling are reported, along with headache, nausea and abdominal discomfort. In studies of intravenous glutathione the medication was generally tolerated, but drug regulators — including the Philippine FDA, where the practice is widespread — have warned that injectable glutathione used at high doses for skin lightening has been associated with serious harms, including Stevens-Johnson syndrome and other severe skin reactions, and with effects on the liver, kidneys and nervous system. Glutathione preparations can release sulfites, which can trigger reactions in people who are sensitive to them. Long-term human safety data are limited.
Injectable glutathione is not prescribed to anyone with a known allergy to glutathione, to sulfites, or to any component of the preparation. It is used cautiously or not at all in people with asthma, particularly sulfite-sensitive asthma, and in significant liver or kidney disease, where safety has not been established. It has not been studied in pregnancy or breastfeeding and is not used in either. Any new rash, blistering, or sores in the mouth or eyes after a dose requires urgent medical attention.
Glutathione is a tripeptide made of cysteine, glutamine, and glycine that functions as the body's most abundant intracellular antioxidant. It neutralizes reactive oxygen species, regenerates other antioxidants such as vitamins C and E, and supports Phase II liver detoxification pathways. Injectable administration bypasses digestive breakdown entirely, delivering glutathione directly into systemic circulation for maximum bioavailability.
Your protocol
Establish your starting point
Weight + Device signals tracked
Suggested updates based on your monitored data
Bloodwork panel rechecked
Explore
Longevity Glutathione Injections deliver the body's master antioxidant directly into the bloodstream to support detoxification, immune health and protection against oxidative stress.
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Mental Health Oxytocin Nasal Spray delivers the body's natural bonding hormone through the nasal mucosa to support emotional connection, social confidence and stress resilience.
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Sexual Wellness Sildenafil is a fast-acting PDE5 inhibitor that increases blood flow to support firm, reliable erections when taken before sexual activity.
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Longevity GHK-Cu is a naturally occurring copper peptide applied to the skin. It is used in topical formulations for skin appearance and repair support.
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Sexual Wellness Tadalafil is a long-acting PDE5 inhibitor that increases blood flow to support firm, lasting erections, with effects that can last up to 36 hours.
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Sexual Wellness PT-141 is a melanocortin receptor agonist that acts on the brain to help increase sexual desire and arousal in both men and women.
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Men's Health Enclomiphene is a selective estrogen receptor modulator that stimulates the body's natural testosterone production in men, supporting hormone balance, fertility, energy and metabolic health.
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Longevity NAD+ Nasal Spray delivers Nicotinamide Adenine Dinucleotide through the nasal mucosa for needle-free cellular energy support and cognitive function.
Learn moreLifelong Optimization
Founding pricing ends at public launch
Frequently Asked Questions
Answers on setup, scale, and support to remove blockers.
Your membership includes four targeted lab panels each year, continuous monitoring from the wearable device of your choice, and continuous monitoring of your smart scale to track weight and body composition. You’ll also receive access to our proprietary health scoring system, built on the American Heart Association’s Life’s Essential 8, which gives you a clear picture of your cardiovascular and metabolic health. Membership comes with ongoing support from a dedicated health coach, custom supplements, and access to prescription treatment through independent licensed providers, all managed directly through your dashboard. Additional devices and monitoring tools can be purchased at discounted member pricing.
OneTwenty is a health optimization membership, not a medical practice. We don't diagnose, treat, or cure medical conditions, and we don't practice medicine.
What we do is give you a clearer picture of your own health. Your membership includes quarterly lab testing, integration of your wearable data, and an AI-powered view of your biomarkers and trends over time. The focus is optimization and prevention for people who are generally healthy and want to stay that way, not the treatment of disease.
Anything clinical, including prescriptions, is delivered by independent, licensed healthcare providers through our telehealth partners. Those providers exercise their own medical judgment and are solely responsible for any evaluation, diagnosis, treatment, or prescription. OneTwenty does not direct or control their clinical decisions.
If you're managing a diagnosed condition, OneTwenty is not a substitute for your physician. We're a complement to the care you already receive, focused on helping you understand and improve the long-term inputs to your health.
Most members can use HSA or FSA funds for their OneTwenty membership. Your membership covers diagnostic lab testing and clinician review, which are generally eligible medical expenses, though final eligibility depends on your specific plan. If you pay with an HSA/FSA card, it works like any other card at checkout. If you don't have a card, or your plan requires documentation, we provide an itemized statement listing the services, the ordering provider, and the amount paid, which you submit to your plan administrator for reimbursement. We can't guarantee your plan's decision, so we recommend confirming with your administrator.
No, OneTwenty prioritizes natural interventions that escalate over time. We will start with lifestyle modifications, then supplements, and only then if needed do we prioritize medication intervention.
We are available in 49 states except for Rhode Island. In New York and New Jersey, there is an increased fee due to collection laws in place that don't allow us to use the Quest Network.
Your privacy and security are foundational to OneTwenty. We run on infrastructure and software built to HIPAA security standards, and we apply the same core safeguards used to protect data in regulated healthcare settings: encryption in transit and at rest, strict role-based access controls, and full audit logging of who accesses your information and when. We never sell your personal health data. You decide what you connect and share, and you can request deletion of your data at any time.
One year on the OneTwenty platform, which covers four lab draws: one comprehensive initial panel to set your baseline, and three custom follow-up panels based on your results. Any additional services are available separately at transparent pricing.
Currently, we do not support direct insurance billing for lab orders. We made this decision to protect our members from unexpected and excessive costs.
Here is why:
The "Medical Necessity" Requirement: Insurance companies typically only cover lab tests that are tied to a specific illness or diagnosis code (ICD-10). Because many of our panels are proactive and focused on longevity (preventive wellness) rather than treating an active sickness, they are frequently rejected by insurers as "investigational" or "not medically necessary."
The Cost Risk: If we submitted these orders to your insurance and they were denied, the lab would bill you their standard "retail price." This retail price can be 5x to 10x higher than the negotiated rates we have secured for you.
Our Solution: By operating on a self-pay basis, we guarantee you access to our heavily discounted wholesale rates, ensuring you know exactly what you are paying upfront with no surprise bills in the mail later.
We are working on it: We understand that using insurance is preferred for basic labs. We are actively working on a solution that will allow us to safely bill insurance for standard preventive tests while keeping advanced longevity markers separate. We hope to introduce this hybrid option in the future.
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