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Quarterly Personalized Lab Panels

An 95+ biomarker baseline, with quarterly retests on the markers that matter.*

Your Devices, Working Together

Smart scales, BP cuffs, sleep and activity trackers, all feeding one protocol.

An AI That Reads Every Signal

Your labs and device readings run through an AI that surfaces what's changing and what to do about it.

  • Total Testosterone

    847

    ng/dL · Lab Result

    Optimal (700–1000 on TRT)

    Primary male androgen driving muscle, libido, energy, and mood. Monitored quarterly on TRT protocol.

  • Body Fat %

    18.4

    % · Smart Scale

    Above 15% target

    Visceral fat aromatizes testosterone into estrogen — lowering body fat directly improves hormonal balance.

  • ApoB

    102

    mg/dL · Lab Result

    Above 90 target

    Counts every artery-clogging particle in your blood — a sharper predictor of cardiovascular risk than LDL alone.

  • LDL Cholesterol

    98

    mg/dL · Lab Result

    Below 100 target

    Primary cardiovascular risk marker. TRT can modestly lower HDL — track LDL trend at every lab draw.

  • Avg Sleep

    7.2

    hrs · Oura Ring

    Below 7.5hr target

    Poor sleep spikes cortisol and suppresses testosterone. Deep sleep is when 70% of nightly GH is secreted.

  • HRV

    68

    ms · resting overnight

    12ms from last week

    Heart rate variability — nervous system resilience. Rises with TRT optimization and recovery improvements.

A Physical That Doesn't Wait
For Your Next Physical.

Every quarter, your bloodwork runs. Every day, your smart devices sync. Every change in your numbers updates your protocol. This is what a physical looks like when it doesn't end.

The Inputs.

Quarterly bloodwork, daily device data, and your full history, flowing into your physical in real time.

  • Quarterly bloodwork at any nearby lab
  • Daily readings from your wearable, smart scale, and BP cuff
  • Nothing to track. Nothing to enter.
Smart ring Smart ring
Smartwatch Smartwatch
Fitness band Fitness band
Body composition scale Body composition scale
Smart scale Smart scale
Blood pressure monitor Blood pressure cuff

How often you test — every 90 days

  1. 01 Year start baseline
  2. 02 Targeted retest Optimization plan
  3. 03 Targeted retest Optimization plan
  4. 04 Targeted retest Next year’s plan

100+ markers drawn. Your targets set.

The Picture.

Your labs, your devices, and your history, read together. You see what's changing before anyone else would notice.

  • One score for the whole body, 0 to 100, from every marker and every device.
  • Each marker on its own trend line, so you see direction, not just a number.
  • Out-of-range flagged in plain language: what it is, what moves it, what to do.
  • Ask the picture anything. It reads your labs and answers from your data.

The Protocol.

A personalized plan based on your biology, in three tiers: lifestyle coaching first, then custom supplement packs, then, where a prescription might help, treatments through independent licensed providers. Updated every quarter as your numbers change.

Tier 1 Lifestyle coaching

Tier 2 Custom supplement packs

Tier 3 Treatments, through independent licensed providers

MEMBERSHIP

The Full
Forever Physical.

Quarterly labs, daily device sync, personalized protocol, in one membership.

$499/ per year

$749/ per year (NY/NJ Only)**

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FEATURES:

  • One Health Score that tells you exactly where you stand
  • Supplement protocol matched to your lab results
  • Syncs with your watch, ring, scale, BP cuff, and CGM
  • AI that reads your labs and device data — and tells you what actually matters
  • Medications and HRT through independent licensed providers, guided by your data
  • Quarterly lab panels — your biomarkers tested and trended 4x a year

HSA/FSA Reimbursement Eligible*

HIPAA Security Standards

~200* lab signals per year. Thousands of smart device signals per day. All in one view.

95+ lab biomarkers annually to start, custom 20+ marker panel retested every quarter, and continuous data from your smart devices. Every signal that moves your biology, captured.

Learn More
28 Biomarkers

Cardiometabolic

32 Biomarkers

Immune & Inflammation

31 Biomarkers

Kidney & Urinary

Lifelong Optimization

Become a
Founding Member

Get started

Founding pricing ends at public launch

Frequently Asked Questions

Clarity before
you commit

Answers on setup, scale, and support to remove blockers.

What’s included in the membership?

Your membership includes four targeted lab panels each year, continuous monitoring from the wearable device of your choice, and continuous monitoring of your smart scale to track weight and body composition. You’ll also receive access to our proprietary health scoring system, built on the American Heart Association’s Life’s Essential 8, which gives you a clear picture of your cardiovascular and metabolic health. Membership comes with ongoing support from a dedicated health coach, custom supplements, and access to prescription treatment through independent licensed providers, all managed directly through your dashboard. Additional devices and monitoring tools can be purchased at discounted member pricing.

Do you treat medical conditions?

OneTwenty is a health optimization membership, not a medical practice. We don't diagnose, treat, or cure medical conditions, and we don't practice medicine.

What we do is give you a clearer picture of your own health. Your membership includes quarterly lab testing, integration of your wearable data, and an AI-powered view of your biomarkers and trends over time. The focus is optimization and prevention for people who are generally healthy and want to stay that way, not the treatment of disease.

Anything clinical, including prescriptions, is delivered by independent, licensed healthcare providers through our telehealth partners. Those providers exercise their own medical judgment and are solely responsible for any evaluation, diagnosis, treatment, or prescription. OneTwenty does not direct or control their clinical decisions.

If you're managing a diagnosed condition, OneTwenty is not a substitute for your physician. We're a complement to the care you already receive, focused on helping you understand and improve the long-term inputs to your health.

Do you accept HSA and FSA?*

Most members can use HSA or FSA funds for their OneTwenty membership. Your membership covers diagnostic lab testing and clinician review, which are generally eligible medical expenses, though final eligibility depends on your specific plan. If you pay with an HSA/FSA card, it works like any other card at checkout. If you don't have a card, or your plan requires documentation, we provide an itemized statement listing the services, the ordering provider, and the amount paid, which you submit to your plan administrator for reimbursement. We can't guarantee your plan's decision, so we recommend confirming with your administrator.

Do I have to take medications?

No, OneTwenty prioritizes natural interventions that escalate over time. We will start with lifestyle modifications, then supplements, and only then if needed do we prioritize medication intervention.

Is OneTwenty available in my state/country?

We are available in 49 states except for Rhode Island. In New York and New Jersey, there is an increased fee due to collection laws in place that don't allow us to use the Quest Network.

Is my health data secure? (HIPAA Standards)

Your privacy and security are foundational to OneTwenty. We run on infrastructure and software built to HIPAA security standards, and we apply the same core safeguards used to protect data in regulated healthcare settings: encryption in transit and at rest, strict role-based access controls, and full audit logging of who accesses your information and when. We never sell your personal health data. You decide what you connect and share, and you can request deletion of your data at any time.

What's included in my membership?

One year on the OneTwenty platform, which covers four lab draws: one comprehensive initial panel to set your baseline, and three custom follow-up panels based on your results. Any additional services are available separately at transparent pricing.

Why can't I use my insurance for these labs?

Currently, we do not support direct insurance billing for lab orders. We made this decision to protect our members from unexpected and excessive costs.

Here is why:

The "Medical Necessity" Requirement: Insurance companies typically only cover lab tests that are tied to a specific illness or diagnosis code (ICD-10). Because many of our panels are proactive and focused on longevity (preventive wellness) rather than treating an active sickness, they are frequently rejected by insurers as "investigational" or "not medically necessary."

The Cost Risk: If we submitted these orders to your insurance and they were denied, the lab would bill you their standard "retail price." This retail price can be 5x to 10x higher than the negotiated rates we have secured for you.

Our Solution: By operating on a self-pay basis, we guarantee you access to our heavily discounted wholesale rates, ensuring you know exactly what you are paying upfront with no surprise bills in the mail later.

We are working on it: We understand that using insurance is preferred for basic labs. We are actively working on a solution that will allow us to safely bill insurance for standard preventive tests while keeping advanced longevity markers separate. We hope to introduce this hybrid option in the future.

Didn't find your answer?

Ask it here. We reply by email, and the good ones end up on this list.

Yur Data

Your Deices

Your Longevity